Research Technician - Mass Spectrometry
Company: Howard Hughes Medical Institute (HHMI)
Location: Chevy Chase
Posted on: April 16, 2024
Job Description:
Primary Work Address: 19700 Helix Drive, Ashburn, VA,
20147Current HHMI Employees, click here to apply via your Workday
account.The Howard Hughes Medical Institute's Janelia Research
Campus is a pioneering research center in Ashburn, Virginia, where
scientists pursue fundamental questions in the life sciences. Our
integrated teams of biologists, computational scientists, and
tool-builders innovate research practices and technologies to solve
biology's deepest mysteries. HHMI launched Janelia in 2006,
establishing an intellectually enriching environment for scientists
to do creative, collaborative, hands-on work. We share our methods,
results, and tools with the scientific community.About the role:We
are seeking an experienced and organized Research Technician III
with experience in proteomics, metabolomics and/or lipidomics to
join our dynamic team. The successful candidate will play a key
role in executing mass spectrometry sample preparation, LC-MS/MS
system operation, data analysis, and contributing to the
development of new methodologies and protocols. This would be an
excellent role for a scientifically minded professional with at
least two years of mass spectrometry experience who enjoys helping
researchers solve their scientific puzzles and contribute their
sound hands-on skills in an outstanding academic research
facility.About Department:The mass spectrometry department at HHMI,
Janelia Research Campus is a new shared resource which is dedicated
to advancing scientific research and innovation in the field of
proteomics, metabolomics, lipidomics and many more. We are equipped
with state-of-the-art instruments and solutions to facilitate the
study of the dynamics, structures, functions, and interactions of
various biomolecules which may correlate to cellular dynamics,
neural and behavioral mechanisms. What we provide:
- A competitive compensation package, with comprehensive health
and welfare benefits.
- A continuous learning environment and opportunities for
professional development and career advancement.
- Collaborative and innovative work environment.
- Chance to make a meaningful impact on scientific research and
discovery.What you'll do:Working under direct supervision of the
department director, you will perform routine and increasingly
sophisticated laboratory tasks and procedures and develop technical
expertise in one or more areas relevant to mass spectrometry.
- Perform sample preparation including biomolecule extractions,
protein digestions, isotope labeling of biomolecules, LC
fractionation, SPE sample cleanup and related sample
purifications.
- Operate and maintain state-of-the-art mass spectrometry
instruments available onsite.
- Analyze proteomics, metabolomcis or lipidomics data using
software packages and bioinformatics tools.
- Keeps accurate and detailed records of experimental procedures,
data analysis results, and assists in identifying and
troubleshooting unexpected results.
- Report on weekly quality control assessments of sample
preparation and instrument performance.
- Contribute to the optimization and validation of proteomics,
metabolomics and lipidomics protocols and methodologies.
- Maintain laboratory inventories and support laboratory
operations.
- May train junior laboratory personnel with respect to proper
laboratory techniques, the use of laboratory equipment, and safety
procedures.
- Perform all other related duties as needed.What you bring:
- Minimum of a bachelor's degree in chemistry, biochemistry or a
closely related field.
- At least 4 years (Bachelor of Science) or 2 years (Master of
Science) of hands-on experience performing proteomics or
metabolomics sample preparation, operating, and/or maintaining
LC-MS/MS systems.
- Proficiency in using mass spectrometer operating software,
particularly Thermo Xcalibur is preferred. Experience in data
analysis software such as Proteome Discoverer, Compound Discoverer,
MaxQuant, and Skyline will be an asset.
- Must have digital literacy to include, but not limited to,
Excel, Word and PowerPoint.
- Enthusiastic and self-motivated individual with the ability to
work independently with minimal supervision.
- Strong organizational skills, customer service skills, and time
management skills.
- Strong verbal and written communication skills.
- Strong attention to detail and recordkeeping skills.
- Ability to function effectively as a member of a team.Physical
RequirementsRemaining in a normal seated or standing position for
extended periods of time; reaching and grasping by extending
hand(s) or arm(s); dexterity to manipulate objects with fingers,
for example using a keyboard; communication skills using the spoken
word; ability to see and hear within normal parameters; ability to
move about workspace. The position requires mobility, including the
ability to move materials weighing up to several pounds (such as a
laptop computer or tablet). Work may involve possible exposure to
malodorous vapors, low dose radiation, contamination by toxic
chemicals and acids and presence of carcinogenic substances or
other hazardous materials.Persons with disabilities may be able to
perform the essential duties of this position with reasonable
accommodation. Requests for reasonable accommodation will be
evaluated on an individual basis.Please Note:This job description
sets forth the job's principal duties, responsibilities, and
requirements; it should not be construed as an exhaustive
statement, however. Unless they begin with the word "may," the
Essential Duties and Responsibilities described above are
"essential functions" of the job, as defined by the Americans with
Disabilities Act.Compensation and Benefits Our employees are
compensated from a total rewards perspective in many ways for their
contributions to our mission, including competitive pay,
exceptional health benefits, retirement plans, time off, and a
range of recognition and wellness programs. Visit our Benefits at
HHMI site to learn more.Compensation Range$52,140.00 (minimum) -
$65,200.00 (midpoint) - $84,700.00 (maximum)Pay Type:AnnualHHMI's
salary structure is developed based on relevant job market data.
HHMI considers a candidate's education, previous experiences,
knowledge, skills and abilities, as well as internal equity when
making job offers. Typically, a new hire for this position in this
location is compensated between the minimum and the midpoint of the
salary range.HHMI is an Equal Opportunity Employer
Keywords: Howard Hughes Medical Institute (HHMI), Severn , Research Technician - Mass Spectrometry, Professions , Chevy Chase, Maryland
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